Fig. 1 · Structure
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4-(((tert-Butoxycarbonyl)amino)methyl)cyclohexane-1-carboxylic acid
PROTAC Linker
4-(((tert-Butoxycarbonyl)amino)methyl)cyclohexane-1-carboxylic acid functions as a PROTAC linker, essential for the construction of proteolysis-targeting chimeras (PROTACs). It facilitates the effective linkage of cellular proteins to E3 ubiquitin ligases, enabling targeted degradation of specific proteins in various biological studies. This compound is pivotal for research applications in targeted protein degradation and drug discovery.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 162046-58-4 |
| Applications | PROTAC Linker |
| Formula | C13H23NO4 |
| Molecular Weight | 257.33 |
| SMILES | O=C(OC(C)(C)C)NCC1CCC(C(=O)O)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.