Fig. 1 · Structure
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4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
Reaction Product
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is a silyl ether derivative of Raloxifene formed through its reaction with tert-butyldimethylsilyl chloride. This compound plays a crucial role in the synthesis of Raloxifene 6-glucuronide, facilitating studies on Raloxifene metabolism and pharmacokinetics. Its utility in chemical research underscores its significance in the exploration of selective estrogen receptor modulators and their applications in therapeutic contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 174264-46-1 |
| Applications | Reaction Product |
| Formula | C34H41NO4SSi |
| Molecular Weight | 587.84 |
| SMILES | O=C(C1=C(C2=CC=C(O[Si](C)(C(C)(C)C)C)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.