Fig. 1 · Structure

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4-Thiazolecarboxylic acid

Intermediate

4-Thiazolecarboxylic acid serves as an important intermediate in organic synthesis. It is utilized in the synthesis of MGL-IN-2, a potent inhibitor of the wild-type monoacylglycerol lipase (MGL) enzyme, demonstrating an inhibitory concentration (IC50) of 0.0121 μM. This compound is valuable in research focused on metabolic diseases, contributing to the advancement of therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3973-08-8
Applications Intermediate
Formula C4H3NO2S
Molecular Weight 129.14
SMILES
O=C(O)C1=CSC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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