42-(2-Tetrazolyl)rapamycin

Catalog No.: A21394

mTOR inhibitor

42-(2-Tetrazolyl)rapamycin

42-(2-Tetrazolyl)rapamycin Chemical Structure

CAS NO. 221877-56-1

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $259.00

Special Price $207.20

10 mg

Regular Price: $446.00

Special Price $356.80

50 mg

Regular Price: $1,325.00

Special Price $1,060.00

100 mg

Regular Price: $2,650.00

Special Price $2,120.00

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Biological Activity

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.35 mL 51.75 mL 103.5 mL
0.5 mM 2.07 mL 10.35 mL 20.7 mL
1 mM 1.03 mL 5.17 mL 10.35 mL
5 mM 0.21 mL 1.03 mL 2.07 mL

*The above data is based on the productmolecular weight 966.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21394
Actions Inhibitor
CAS No. 221877-56-1
Formula C52H79N5O12
M. Wt 966.21
Purity >98%
SMILES [H][[email protected]]1(C(O[[email protected]@]([[email protected]@H](C[[email protected]]2C[[email protected]@H](OC)[[email protected]@H](N3N=CN=N3)CC2)C)([H])CC([[email protected]@H](/C=C([[email protected]@H](O)[[email protected]]4OC)\C)C)=O)=O)N(C(C([[email protected]@]5(O)[[email protected]](C)CC[[email protected]](C[[email protected]@H](/C(C)=C/C=C/C=C/[[email protected]@H](C)C[[email protected]@H](C)C4=O)OC)([H])O5)=O)=O)CCCC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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