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5-3-[(2,2,2-Trifluoroacetyl)amino-1-propyn-1-yl]uridine

Thymidine Analog

5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound can effectively label cells, allowing for the tracking of DNA synthesis in various biological contexts. Additionally, it serves as a click chemistry reagent due to its alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its utility in DNA research and labeling makes it a valuable tool for cell biology studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	120609-05-4
Applications	Thymidine Analog
Formula	C₁₄H₁₄F₃N₃O₇
Molecular Weight	393.27
SMILES	O[C@@H]1[C@H](O)[C@H](N2C(NC(C(C#CCNC(C(F)(F)F)=O)=C2)=O)=O)O[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.