5,7-Dihydroxychromone functions as a caspase activator and exhibits neuroprotective properties by activating the Nrf2/ARE signaling pathway. This compound effectively mitigates oxidative stress and apoptosis induced by 6-hydroxydopamine (6-OHDA) in SH-SY5Y cells. Additionally, 5,7-Dihydroxychromone reduces the expression of activated caspase-3, caspase-9, and cleaved PARP, making it a valuable tool for studying neuroprotection and apoptosis in cellular models.
5,7-Dihydroxychromone functions as a caspase activator and exhibits neuroprotective properties by activating the Nrf2/ARE signaling pathway. This compound effectively mitigates oxidative stress and apoptosis induced by 6-hydroxydopamine (6-OHDA) in SH-SY5Y cells. Additionally, 5,7-Dihydroxychromone reduces the expression of activated caspase-3, caspase-9, and cleaved PARP, making it a valuable tool for studying neuroprotection and apoptosis in cellular models.
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