Fig. 1 · Structure
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5-A-RU-PABC-Val-Cit-Fmoc
5-A-RU Prodrug
5-A-RU-PABC-Val-Cit-Fmoc is a prodrug of the potent MAIT cell activator, 5-A-RU. This compound plays a critical role in immune modulation, facilitating the activation of mucosal-associated invariant T (MAIT) cells through its interaction with small molecules, including glyoxal and methylglyoxal, which are products of metabolic processes. It is primarily utilized in research areas focused on immune response and microbial interactions, highlighting its potential in developing therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2677841-58-4 |
| Applications | 5-A-RU Prodrug |
| Formula | C43H53N9O13 |
| Molecular Weight | 903.93 |
| SMILES | O=C(NC1=CC=C(C=C1)COC(NC2=C(NC(NC2=O)=O)NC[C@@H]([C@@H]([C@@H](CO)O)O)O)=O)[C@@H](NC([C@@H](NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C(C)C)=O)CCCNC(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.