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5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine

Thymidine Analog

5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine is a thymidine analog that displays insertional activity towards replicated DNA, making it valuable for cell labeling and the tracking of DNA synthesis. This compound features an azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, facilitating its use in bioorthogonal labeling applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2305416-08-2
Applications	Thymidine Analog
Formula	C₃₂H₂₇N₅O₉
Molecular Weight	625.58
SMILES	O=C(NC(C(CN=[N+]=[N-])=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@@]2(C)OC(C5=CC=CC=C5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.