5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog that functions as a radiosensitizer, particularly effective in EMT6 tumor cell lines. This compound serves as a valuable reagent in click chemistry, possessing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds that possess DBCO or BCN reactive groups, making it a versatile tool for biochemical research and molecular labeling applications.
5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog that functions as a radiosensitizer, particularly effective in EMT6 tumor cell lines. This compound serves as a valuable reagent in click chemistry, possessing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds that possess DBCO or BCN reactive groups, making it a versatile tool for biochemical research and molecular labeling applications.
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