Fig. 1 · Structure
Documents & Downloads
5-Azidomethyl-2'-deoxyuridine
Purine Nucleoside Analog
5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog that functions as a radiosensitizer, particularly effective in EMT6 tumor cell lines. This compound serves as a valuable reagent in click chemistry, possessing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds that possess DBCO or BCN reactive groups, making it a versatile tool for biochemical research and molecular labeling applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 59090-48-1 |
| Applications | Purine Nucleoside Analog |
| Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
| Synonyms | 5-AmdU; α-Azidothymidine |
| SMILES | O=C(C(CN=[N+]=[N-])=CN1[C@H]2C[C@H](O)[C@@H](CO)O2)NC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.