Fig. 1 · Structure
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5-Bromopentanoyl chloride
PROTAC Linker
5-Bromopentanoyl chloride is a versatile PROTAC linker primarily utilized in the synthesis of PROTACs, facilitating the targeted degradation of specific proteins. This compound serves as a key component in the design of PROTAC ATR degrader-2, promoting efficient target protein ubiquitination and subsequent proteasomal degradation. Its application in chemical biology research supports the development of innovative therapeutic strategies aimed at regulating protein levels within cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4509-90-4 |
| Applications | PROTAC Linker |
| Formula | C5H8BrClO |
| Molecular Weight | 199.47 |
| SMILES | O=C(Cl)CCCCBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.