Fig. 1 · Structure
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(5-Bromopentyl)oxy(tert-butyl)dimethylsilane
PROTAC Linker
[(5-Bromopentyl)oxy](tert-butyl)dimethylsilane serves as a powerful PROTAC linker, facilitating the development of PROTAC molecules for targeted protein degradation. Its structure enables efficient conjugation, enhancing the efficacy and biological activity of PROTACs in various cellular contexts. This compound is particularly valuable for researchers exploring therapeutic strategies that involve targeted modulation of protein levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 85514-43-8 |
| Applications | PROTAC Linker |
| Formula | C11H25BrOSi |
| Molecular Weight | 281.31 |
| SMILES | BrCCCCCO[Si](C)(C)C(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.