Fig. 1 · Structure

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5′-Guanylyl methylenediphosphonate sodium

GTP Analogue

5′-Guanylyl methylenediphosphonate sodium is a GTP analogue that acts as a specific, competitive inhibitor of GTP-dependent processes in protein synthesis. By mimicking GTP, it disrupts nucleotide binding, thereby affecting the translation mechanism in cells. This reagent is valuable for researchers investigating protein biosynthesis pathways and studying the regulatory roles of GTP in various cellular functions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 10470-57-2
Applications GTP Analogue
Formula C11H15N5Na3O13P3
Molecular Weight 587.15
Synonyms β,γ-Methylene-GTP sodium
SMILES
O[C@H]1[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COP(OP(CP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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