5-HT2C agonist-9

Catalog No.: A29782
5-HT2C Agonist
5-HT2C agonist-9 is a high-affinity agonist for the 5-HT2C receptor, displaying an EC50 of 1.4 nM for human 5-HT2C. This compound serves as a valuable tool in the investigation of various neuropsychiatric disorders, including depression, drug addiction, alcoholism, post-traumatic stress disorder (PTSD), and neuropathic pain. Its potent activity at the 5-HT2C receptor may facilitate research aimed at understanding the therapeutic potentials within these conditions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5-HT2C agonist-9 is a high-affinity agonist for the 5-HT2C receptor, displaying an EC50 of 1.4 nM for human 5-HT2C. This compound serves as a valuable tool in the investigation of various neuropsychiatric disorders, including depression, drug addiction, alcoholism, post-traumatic stress disorder (PTSD), and neuropathic pain. Its potent activity at the 5-HT2C receptor may facilitate research aimed at understanding the therapeutic potentials within these conditions.
Product Information
Catalog NumA29782
FormulaC13H17FN2O
Molecular Weight236.29
CAS Number2873459-44-8
SMILESCC1=C2NC=C(C2=C(C=C1F)O)CCN(C)C
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