Fig. 1 · Structure
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5-Hydroxyindole
Tryptophan Metabolite
5-Hydroxyindole is a tryptophan metabolite that serves as a potent activator of α7 nicotinic acetylcholine receptors and influences intestinal L-type calcium channels. It modulates the desensitization of 5-HT3 receptor-mediated ion currents, making it relevant in neurobiological studies. This compound is utilized in research on neuroblastoma, schizophrenia, and disorders related to intestinal motility.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1953-54-4 |
| Applications | Tryptophan Metabolite |
| Formula | C8H7NO |
| Molecular Weight | 133.15 |
| SMILES | OC1=CC2=C(C=C1)NC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.