5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog that serves as an effective inhibitor of DNA replication in various human leukemia cell lines, exhibiting IC50 values ranging from 1.7 to 5.8 μM. This compound has been shown to extend the survival of mice with L1210 leukemia, demonstrating its potential in cancer treatment research. Its unique properties make it a valuable tool for investigating mechanisms of cell replication and the biology of leukemia.
5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog that serves as an effective inhibitor of DNA replication in various human leukemia cell lines, exhibiting IC50 values ranging from 1.7 to 5.8 μM. This compound has been shown to extend the survival of mice with L1210 leukemia, demonstrating its potential in cancer treatment research. Its unique properties make it a valuable tool for investigating mechanisms of cell replication and the biology of leukemia.
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