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5-hydroxymethyl tolterodine (PNU 200577)

Catalog No.: A11166

muscarinic receptor antagonist

5-hydroxymethyl tolterodine (PNU 200577)

5-hydroxymethyl tolterodine (PNU 200577) Chemical Structure

CAS NO. 207679-81-0

5-hydroxymethyl tolterodine is a metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$280.00
50 mg
$680.00
100 mg
$1,050.00
10mM * 1mL in DMSO
$168.00
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Biological Activity

5-hydroxymethyl tolterodine is a metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Targets
mAChR
0.84 nM(Kb)
In vitro DMSO 60 mg/mL (175.69 mM)
Water Insoluble
Ethanol 60 mg/mL (175.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.28 mL 146.42 mL 292.83 mL
0.5 mM 5.86 mL 29.28 mL 58.57 mL
1 mM 2.93 mL 14.64 mL 29.28 mL
5 mM 0.59 mL 2.93 mL 5.86 mL

*The above data is based on the productmolecular weight 341.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11166
Actions Antagonist
CAS No. 207679-81-0
Formula C22H31NO2
M. Wt 341.49
Purity >98%
Synonyms (R)-5-Hydroxymethyl tolterodine
SMILES CC(C)N(CC[[email protected]](C1=CC=CC=C1)C2=C(C=CC(=C2)CO)O)C(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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