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5-Me-3’-dU-2’-phosphoramidite

Catalog No.: A55752
Purine Nucleoside Analog
5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog designed to inhibit DNA synthesis, contributing to its antitumor activity. This compound demonstrates effectiveness in targeting indolent lymphoid malignancies, mediating cellular apoptosis and disrupting cellular proliferation. Its applications extend to cancer research, particularly in exploring therapeutic strategies against hematological malignancies.
5-Me-3’-dU-2’-phosphoramidite 142103-12-6 Purine Nucleoside Analog
Grouped product items
Size Price Stock Qty
5mg
$55.00
In stock
10mg
$85.00
In stock
25mg
$135.00
In stock
50mg
$200.00
In stock
100mg
$295.00
In stock
250mg
$485.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog designed to inhibit DNA synthesis, contributing to its antitumor activity. This compound demonstrates effectiveness in targeting indolent lymphoid malignancies, mediating cellular apoptosis and disrupting cellular proliferation. Its applications extend to cancer research, particularly in exploring therapeutic strategies against hematological malignancies.
Product Information
Catalog NumA55752
FormulaC40H49N4O8P
Molecular Weight744.81
CAS Number142103-12-6
SMILESO=C(C(C)=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)=O
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DNA Damage > Nucleoside Antimetabolite/Analog