Fig. 1 · Structure
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5-Methylcytosine hydrochloride
DNA Modification
5-Methylcytosine hydrochloride is an important DNA modification that targets methylation processes in prokaryotes and eukaryotes. It is primarily involved in the symmetrical methylation of CpG dinucleotides, which plays a critical role in stabilizing tRNA and rRNA structures and influencing mRNA translation. This compound can also undergo oxidation to produce 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine. 5-Methylcytosine hydrochloride is widely utilized in epigenetics, developmental biology, and research related to diseases, including colorectal cancer and hepatocellular carcinoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58366-64-6 |
| Applications | DNA Modification |
| Formula | C5H8ClN3O |
| Molecular Weight | 161.59 |
| SMILES | O=C1N=CC(C)=C(N)N1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.