Fig. 1 · Structure
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5-Methylcytosine
DNA Modification
5-Methylcytosine primarily targets DNA modification and is a well-characterized epigenetic marker in both prokaryotic and eukaryotic organisms. This modified nucleotide is essential for forming symmetrical methylation patterns on CpG dinucleotides, influencing tRNA and rRNA stabilization as well as mRNA translation processes. Additionally, 5-Methylcytosine can be oxidized to produce derivatives such as 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine. It proves invaluable for research in epigenetics, developmental biology, and the exploration of various diseases, including colorectal cancer and hepatocellular carcinoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 554-01-8 |
| Applications | DNA Modification |
| Formula | C5H7N3O |
| Molecular Weight | 125.13 |
| SMILES | O=C1N=CC(C)=C(N)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.