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5-Nitro BAPTA tetramethyl ester

Calcium Chelator

5-Nitro BAPTA tetramethyl ester is a potent calcium chelator that effectively modulates intracellular calcium levels. It is utilized in the synthesis of two-photon probes, enabling real-time imaging and monitoring of calcium ion fluctuations and calcium waves in liver tissues at depths of 100-300 μm over extended durations of 1100-4000 seconds. Additionally, when combined with the fluorescent compound 2-Me-substituted TM, it can be employed to create a red fluorescent probe known as CaTM-2 AM, enhancing its utility in calcium-related biological research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	172646-43-4
Applications	Calcium Chelator
Formula	C₂₆H₃₁N₃O₁₂
Molecular Weight	577.54
SMILES	O=C(OC)CN(C1=CC=CC=C1OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(OC)=O)CC(OC)=O)CC(OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.