Fig. 1 · Structure

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5'-O-DMTr-2'-O-TBDMS-5-Me-U-3'-CE Phosphoramidite

Nucleoside Analog

5'-O-DMTr-2'-O-TBDMS-5-Me-U-3'-CE Phosphoramidite is a modified nucleoside analog designed for RNA oligonucleotide synthesis. The presence of protecting groups enhances the stability and compatibility during the synthesis process, enabling efficient incorporation into RNA strands. This reagent is ideal for use in various applications, including the development of RNA-based therapeutics and biotechnological research involving RNA manipulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 159639-78-8
Applications Nucleoside Analog
Formula C46H63N4O9PSi
Molecular Weight 875.07
SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](O[Si](C(C)(C)C)(C)C)[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)OCCC#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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