Fig. 1 · Structure
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5-Ph-IAA
AID2 Ligand
5-Ph-IAA is a ligand that specifically interacts with the auxin-inducible degron 2 (AID2) system, in conjunction with the OsTIR1 (F74G) mutant. This compound facilitates the rapid and efficient degradation of mAID-fused proteins, enabling the investigation of protein function in live cells. 5-Ph-IAA is particularly useful in studies related to protein turnover and regulation, offering insights into cellular processes such as tumor suppression. Its application in research enhances the understanding of protein dynamics in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 168649-23-8 |
| Applications | AID2 Ligand |
| Formula | C16H13NO2 |
| Molecular Weight | 251.28 |
| SMILES | O=C(O)CC1=CNC2=C1C=C(C3=CC=CC=C3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.