Fig. 1 · Structure
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5(Z),11(Z),14(Z)-Eicosatrienoic acid
Apolipoprotein Inhibitor
5(Z),11(Z),14(Z)-Eicosatrienoic acid, also known as Sciadonic acid, acts as an apolipoprotein inhibitor. This polyunsaturated fatty acid, derived from maritime pine seed oil and certain gymnospermae, has demonstrated the ability to lower high-density lipoprotein and ApoA1 levels in transgenic mice models. In vitro studies reveal its role in reducing cholesterol efflux, while its methyl ester form exhibits anti-inflammatory properties through the displacement of arachidonic acid from phospholipid pools, subsequently decreasing levels of inflammatory mediators such as prostaglandin E2 and leukotrienes. This compound holds potential for research in lipid metabolism and inflammatory response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 7019-85-4 |
| Applications | Apolipoprotein Inhibitor |
| Formula | C20H34O2 |
| Molecular Weight | 306.48 |
| Synonyms | Sciadonic acid |
| SMILES | O=C(CCC/C=C/CCCC/C=C/C/C=C/CCCCC)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.