Fig. 1 · Structure
Documents & Downloads
5α-Hydroxy-6-keto cholesterol
β-epoxide Metabolite
5α-Hydroxy-6-keto cholesterol is a significant metabolite of β-epoxide (5α,6β-epoxycholesterol) generated during the exposure of human bronchial epithelial cells (16-HBE) to ozone. This compound acts as an inhibitor of cholesterol synthesis, exhibiting an IC50 value of 350 nM. It is valuable for research into oxidative stress and its effects on cholesterol metabolism in respiratory epithelial cells.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 13027-33-3 |
| Applications | β-epoxide Metabolite |
| Formula | C27H46O3 |
| Molecular Weight | 418.65 |
| SMILES | C[C@@]12[C@]3([H])[C@](CC([C@]1(C[C@H](CC2)O)O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.