Fig. 1 · Structure
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6(5H)-Phenanthridinone
PARP-1 Inhibitor
6(5H)-Phenanthridinone is a potent inhibitor of PARP-1, a key enzyme involved in DNA repair processes. This compound exhibits significant immunomodulatory effects and has been shown to inhibit cell proliferation. It is employed in cancer research to explore therapeutic strategies targeting DNA repair pathways and to enhance the efficacy of chemotherapeutic agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1015-89-0 |
| Applications | PARP-1 Inhibitor |
| Formula | C13H9NO |
| Molecular Weight | 195.22 |
| SMILES | O=C1NC2=CC=CC=C2C3=C1C=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.