Fig. 1 · Structure

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6-epi Doxycycline

Doxycycline Epimer

6-Epi Doxycycline is the C-6 epimer of Doxycycline, resulting from epimerization under specific conditions such as elevated temperature, pH variation, or high humidity. This compound serves as a critical reference standard for the detection and quantification of impurities in pharmaceutical formulations. Its utility extends to analytical studies assessing the stability and degradation pathways of doxycycline and similar antibiotics.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3219-99-6
Applications Doxycycline Epimer
Formula C22H24N2O8
Molecular Weight 444.43
SMILES
O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4[C@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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