Fig. 1 · Structure
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6-Hydroxymelatonin
Melatonin Metabolite
6-Hydroxymelatonin is a primary metabolite of melatonin, formed via metabolism by CYP1A2, with the ability to penetrate the blood-brain barrier. This compound exhibits potent free radical scavenging and antioxidant properties, effectively mitigating oxidative damage induced by various neurotoxins. Additionally, it can induce oxidative DNA damage in the presence of copper ions through a "non-quinone" redox cycling mechanism, making it a valuable tool for research into neuroprotective strategies and oxidative stress-related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2208-41-5 |
| Applications | Melatonin Metabolite |
| Formula | C13H16N2O3 |
| Molecular Weight | 248.28 |
| SMILES | CC(NCCC1=CNC2=C1C=C(OC)C(O)=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.