Fig. 1 · Structure

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6-Iodohex-1-yne

PROTAC Linker

6-Iodohex-1-yne is a versatile linker for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the effective recruitment of an E3 ligase to target proteins for ubiquitination and subsequent degradation. It plays a crucial role in various research applications, including the development of targeted protein degradation strategies in therapeutic contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2468-56-6
Applications PROTAC Linker
Formula C6H9I
Molecular Weight 208.04
SMILES
ICCCCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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