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7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine

Purine Nucleoside Analog

7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, incorporating an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This versatile profile makes it valuable for various biochemical research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2389988-55-8
Applications	Purine Nucleoside Analog
Formula	C₁₃H₁₄FN₅O₅
Molecular Weight	339.28
SMILES	OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C(N(CC#C)C3=C2NC(N)=NC3=O)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.