Fig. 1 · Structure
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7-Amino-3-chloro cephalosporanic acid
Cefaclor Intermediate
7-Amino-3-chloro cephalosporanic acid (7-ACCA) serves as a critical intermediate in the synthesis of the antibiotic cefaclor, a second-generation cephalosporin. It exhibits effective antibacterial activity against a range of Gram-positive and Gram-negative bacteria. The compound is primarily utilized in pharmaceutical research for the development of cephalosporin antibiotics, making it a valuable reagent in medicinal chemistry and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 53994-69-7 |
| Applications | Cefaclor Intermediate |
| Formula | C7H7ClN2O3S |
| Molecular Weight | 234.66 |
| Synonyms | 7-ACCA |
| SMILES | O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](N)C1=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.