7-Aminomethyl-10-methyl-11-fluoro camptothecin

Catalog No.: A41039
ADC Cytotoxin
7-Aminomethyl-10-methyl-11-fluoro camptothecin is a potent cytotoxin targeting cancer cells through its mechanism of acting as a topoisomerase inhibitor. This compound serves as an essential intermediate for the synthesis of camptothecin-based antibody-drug conjugates (ADCs), which are designed to deliver targeted therapeutic agents to tumor cells. Its applications in cancer research support the development of innovative treatments aimed at improving the efficacy of chemotherapy while reducing systemic toxicity.
Grouped product items
Size Price Stock Qty
1mg
$200.00
In stock
5mg
$510.00
In stock
10mg
$830.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description7-Aminomethyl-10-methyl-11-fluoro camptothecin is a potent cytotoxin targeting cancer cells through its mechanism of acting as a topoisomerase inhibitor. This compound serves as an essential intermediate for the synthesis of camptothecin-based antibody-drug conjugates (ADCs), which are designed to deliver targeted therapeutic agents to tumor cells. Its applications in cancer research support the development of innovative treatments aimed at improving the efficacy of chemotherapy while reducing systemic toxicity.
Product Information
Catalog NumA41039
FormulaC22H20FN3O4
Molecular Weight409.41
CAS Number2378616-23-8
SMILESNCC1=C2C(C(N3C2)=CC([C@]4(CC)O)=C(C3=O)COC4=O)=NC5=CC(F)=C(C=C51)C
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