Fig. 1 · Structure
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7-Azido-4-methylcoumarin
H2S Probe
7-Azido-4-methylcoumarin operates primarily as a fluorescent probe for hydrogen sulfide (H2S). This compound is utilized for its high sensitivity in assessing cystathionine β-synthase activity. With an azide functional group, it is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC) when interacting with alkyne-containing molecules or those featuring DBCO or BCN groups. Its applications extend to biological research exploring H2S signaling and related metabolic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 95633-27-5 |
| Applications | H2S Probe |
| Formula | C10H7N3O2 |
| Molecular Weight | 201.18 |
| SMILES | [N-]=[N+]=NC1=CC(OC(C=C2C)=O)=C2C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.