Coumarin Dyes
Browse coumarin dyes and derivatives identified in product-specific catalog or supplier information. Compare individual product specifications and package options.
The family grouping does not establish a shared excitation wavelength, enzyme specificity or labeling function. Review the documented use of the exact derivative.
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- Cat. No.
- A13077
Coumarin 30
Synonyms: Coumarin-30,Coumarin30
Coumarin 30 is useful as laser dye. Efficient laser dye for pulsed and CW operation.
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- Cat. No.
- A13365
3-Cyano-7-ethoxycoumarin
Synonyms: 7-Ethoxycoumarin-3-carbonitrile
3-Cyano-7-ethoxycoumarin is a fluorogenic substrate suitable for the continuous determination of cytochrome P450 mixed-function monooxygenases. It is a fluorescent probe useful in microsomal dealkylase studies.
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- Cat. No.
- A16973
7-Amino-4-methylcoumarin
Synonyms: Coumarin 120; AMC
7-Amino-4-methylcoumarin is a fluorogenic reagent and antibacterial, antifungal agent. It os used as reference compound in enzyme assays.
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- Cat. No.
- A22355
Coumarin-3-carboxylic Acid
Synonyms: 2-Oxochromene-3-carboxylic acid
Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line.
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- Cat. No.
- A24560
Coumarin 6
Coumarin 6 is a fluorescent dye commonly used as a probe in drug delivery research. It serves as a tracer in microparticle and nanoparticle delivery systems, enabling *in vivo* tracking, cellular uptake analysis, and transport mechanism studies. Coumarin 6 exhibits strong fluorescence with excitation and emission maxima at λexc = 450 nm and λem = 505 nm, respectively, making it an ideal marker for evaluating drug distribution and release profiles in biological systems.
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- Cat. No.
- A26329
Coumarin-SAHA
Coumarin-SAHA is a fluorescent probe designed to investigate the binding affinities (kd) and dissociation off-rates (koff) of histone deacetylase 8 (HDAC8) inhibitor complexes. This compound is particularly valuable in research applications focused on epigenetic regulation and cancer biology. The fluorescent properties of Coumarin-SAHA enable real-time monitoring of molecular interactions, enhancing the understanding of HDAC functions and their role in disease mechanisms.
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- Cat. No.
- A43477
Gly-Arg-AMC
Gly-Arg-AMC is a peptide substrate specifically designed for the Dipeptidyl Peptidase I (DPAP1) enzyme. This compound exhibits high specificity for DPAP1, facilitating the study of proteolytic processing and enzyme activity. It serves as a valuable tool in biochemical research focused on protease function and related signaling pathways.
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- Cat. No.
- A43561
Pro-Arg-AMC
Pro-Arg-AMC is a peptide substrate specifically designed for DPAP1 (dipeptidyl peptidase I). This compound is utilized in biochemical assays to study the enzymatic activity of DPAP1, playing a crucial role in understanding protein processing and activation pathways. Its monitoring can provide insights into various physiological processes and pathologies where DPAP1 is implicated.
Out of stock
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- Cat. No.
- A44318
7-Dimethylaminocoumarin-4-acetic acid
7-Dimethylaminocoumarin-4-acetic acid is a fluorescent dye that emits high-intensity fluorescence upon excitation. It is commonly used in biological imaging and assay development due to its excellent photostability and water solubility. This compound can facilitate the study of cellular processes and molecular interactions, making it valuable for researchers in the fields of biochemistry and molecular biology.
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- Cat. No.
- A44409
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a fluorescent dye that exhibits pH-dependent and environment-sensitive fluorescence properties. This compound serves as a blue fluorophore and is extensively utilized in the preparation of bioconjugates for various imaging applications. Its distinctive fluorescent characteristics make it suitable for studies requiring precise visual tracking or labeling in biological research.
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- Cat. No.
- A44450
Coumarin-PEG2-endoBCN
Coumarin-PEG2-endoBCN is a fluorescent dye that incorporates a coumarin fluorophore, functioning as a versatile click chemistry reagent. It exhibits strong fluorescence properties, making it suitable for various biological imaging applications. This compound can be utilized in the labeling of biomolecules, facilitating studies in cellular dynamics and molecular interactions.
Out of stock
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- Cat. No.
- A44462
Z-Gly-Pro-AMC
Z-Gly-Pro-AMC is a fluorogenic substrate specifically targeted for prolyl endopeptidase. Upon hydrolysis, it releases the highly fluorescent compound 7-Amino-4-methylcoumarin, which exhibits excitation and emission maxima at 380 nm and 465 nm, respectively. This substrate is primarily utilized in enzymatic assays and studies involving prolyl endopeptidase activity, making it valuable for research in enzyme kinetics and related fields.
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- Cat. No.
- A44465
Z-Gly-Gly-Arg-AMC
Z-Gly-Gly-Arg-AMC is a thrombin-specific chromogenic substrate that enables the study of thrombin generation in platelet-rich plasma (PRP) and platelet-poor plasma (PPP). This fluorogenic substrate has an excitation/emission maximum at 390/480 nm, facilitating sensitive detection of thrombin activity. It is widely utilized in research applications focused on coagulation and thrombotic disorders.
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- Cat. No.
- A44484
L-Leucine-7-amido-4-methylcoumarin hydrochloride
Synonyms: Leu-AMC hydrochloride
L-Leucine-7-amido-4-methylcoumarin hydrochloride is a fluorogenic substrate specifically designed for leucine aminopeptidase 3 (LAP3). This substrate exhibits strong fluorescent properties, enabling sensitive detection of LAP3 enzymatic activity. It is suitable for use in in vitro assays aimed at investigating LAP3 function and potential inhibition, making it a valuable tool for biochemical and pharmacological research.
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- Cat. No.
- A44544
Ac-DNLD-AMC
Ac-DNLD-AMC is a fluorogenic substrate specifically designed for the detection of caspase-3 activity. Upon cleavage by this enzyme, Ac-DNLD-AMC releases the fluorescent moiety 7-amino-4-methylcoumarin (AMC), enabling sensitive quantification of caspase-3 enzymatic activity. This reagent is valuable in apoptosis research and the study of cellular processes involving programmed cell death.
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- Cat. No.
- A44545
7-Hydroxycoumarinyl-γ-linolenate
7-Hydroxycoumarinyl-γ-linolenate serves as a fluorogenic substrate specifically for cytosolic phospholipase A2 (cPLA2). This compound is utilized to assess and monitor the enzymatic activity of cPLA2 in various biological systems. Its ability to generate fluorescence upon cleavage allows for sensitive detection and quantification, making it valuable in studies related to inflammation and lipid signaling pathways.
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- Cat. No.
- A44563
Glut-Phe-AMC
Glut-Phe-AMC is a fluorescent dye primarily used for monitoring proteolytic activity. This substrate is cleaved by proteases, releasing the fluorescent aminomethylcoumarin (AMC) moiety, which allows for sensitive detection in various biological assays. Its application is particularly valuable in studies involving enzyme activity, protein degradation, and cellular processes. Glut-Phe-AMC serves as an essential tool for researchers exploring protease functions in numerous biological contexts.
Out of stock
All 3 sizes -
- Cat. No.
- A44841
7-Amino-4-(trifluoromethyl)coumarin
Synonyms: Coumarin 151; AFC
7-Amino-4-(trifluoromethyl)coumarin is a fluorescent dye primarily utilized for the sensitive detection of proteinases. It emits fluorescence when excited at 400 nm, with a peak emission at 490 nm. This compound is ideal for applications in biochemical assays and imaging studies, enhancing the visualization of enzymatic activity in various biological systems.
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- Cat. No.
- A44883
MCA
Synonyms: 7-Methoxycoumarin-4-acetic acid
MCA (7-Methoxycoumarin-4-acetic acid) is a fluorescent dye targeting platelet-activating factor (PAF). It is utilized in high-performance liquid chromatography with fluorescent detection to quantify PAF levels. Additionally, MCA can be employed to modify Förster resonance energy transfer (FRET) peptide substrates, facilitating the analysis of protease activities in various biological research applications.
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- Cat. No.
- A44932
Coumarin-C2-exo-BCN
Coumarin-C2-exo-BCN is a fluorochrome dye derivative of coumarin that features the lipophilic bidentate macrocyclic ligand exo-BCN. This compound enables the formation of macrocyclic complexes and plays a significant role in click chemistry, where it reacts with azide-containing molecules to produce stable triazoles without the need for catalysts. Coumarin-C2-exo-BCN is valuable in biological imaging and tracking applications, facilitating the study of molecular interactions and dynamics in various research contexts.
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- Cat. No.
- A44942
AMCA,SE
Synonyms: 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a fluorescent dye with amine-reactive labeling capabilities. It is commonly utilized in biological research for the conjugation of proteins and antibodies, facilitating visualization in fluorescence microscopy and flow cytometry. This reagent is ideal for studying cellular processes and interactions through targeted fluorescent labeling.
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- Cat. No.
- A44955
7-Diethylamino-4-methylcoumarin
7-Diethylamino-4-methylcoumarin is a fluorescent laser dye that exhibits strong photostability and high quantum yield, making it suitable for various applications in fluorescence microscopy and spectroscopy. This compound is primarily used for labeling and imaging in biological research, enabling the visualization of cellular components and processes. Its unique properties enhance sensitivity and resolution in experimental setups.
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- Cat. No.
- A44958
Coumarin hydrazine
Coumarin hydrazine is a fluorescent chemical probe targeting cellular protein- and lipid-bound carbonyls, exhibiting excitation and emission wavelengths of λex=420–450/λem=468 nm. This reagent is valuable for the detection and quantification of carbonyl species in biological samples. Its specificity and sensitivity make it suitable for applications in cell biology and biochemical studies involving oxidative stress and carbonylation.
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- Cat. No.
- A44997
3-Carboxy-7-Hydroxycoumarin
3-Carboxy-7-Hydroxycoumarin is a fluorescent dye that is excitable by UV light. This compound exhibits strong fluorescence properties, making it suitable for various biological imaging applications. It can be utilized in studies involving cellular fluorescence, allowing for visualizing and tracking biological processes in live and fixed specimens. Its chemical structure enables effective labeling and detection in fluorescence microscopy and other analytical techniques.
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