Fig. 1 · Structure
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7-Methyl-6-thioguanosine
Chromogenic Substrate
7-Methyl-6-thioguanosine (MESG) serves as a chromogenic substrate for purine nucleoside phosphorylase, converting to 7-methyl-6-thioguanine in the presence of inorganic phosphate. This compound is instrumental in quantifying inorganic phosphate levels, making it valuable for studies involving nucleotide metabolism. Additionally, MESG can be utilized to assess the activity of purine nucleoside phosphorylase and protein phosphatases in various biochemical assays, facilitating research in enzymology and cellular signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 55727-10-1 |
| Applications | Chromogenic Substrate |
| Formula | C11H15N5O4S |
| Molecular Weight | 313.33 |
| Synonyms | MESG |
| SMILES | S=C1NC(N)=NC2=C1[N+](C)=CN2[C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.