Fig. 1 · Structure

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7-(Triethylsilyl)baccatin III

Taxol Intermediate

7-(Triethylsilyl)baccatin III serves as an intermediate in the synthesis of the antitumor agent Paclitaxel. This compound plays a critical role in the production of Paclitaxel, a widely utilized chemotherapeutic agent effective against various cancers. Its use in research facilitates the development of improved formulations and derivatives of Paclitaxel for enhanced therapeutic efficacy.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 115437-21-3
Applications Taxol Intermediate
Formula C37H52O11Si
Molecular Weight 700.89
Synonyms 7-O-(Triethylsilyl)baccatin III
SMILES
CC(O[C@]12[C@]3([H])[C@@]([C@H](C[C@@]1([H])OC2)O[Si](CC)(CC)CC)(C([C@@H](C4=C(C)[C@@H](O)C[C@@](O)([C@H]3OC(C5=CC=CC=C5)=O)C4(C)C)OC(C)=O)=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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