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7α,25-Dihydroxycholesterol intermediate-1

Catalog No.: A60236
Intermediate
7α,25-Dihydroxycholesterol intermediate-1 is a crucial synthetic intermediate in the production of 7α,25-Dihydroxycholesterol. This compound functions as a ligand for the orphan G protein-coupled receptor EBI2 (GPR183), playing a significant role in immune system regulation and cellular signaling pathways. Its applications extend to the development of PROTACs, enabling targeted protein degradation in research and therapeutic contexts.
7α,25-Dihydroxycholesterol intermediate-1 1326612-12-7 Intermediate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description7α,25-Dihydroxycholesterol intermediate-1 is a crucial synthetic intermediate in the production of 7α,25-Dihydroxycholesterol. This compound functions as a ligand for the orphan G protein-coupled receptor EBI2 (GPR183), playing a significant role in immune system regulation and cellular signaling pathways. Its applications extend to the development of PROTACs, enabling targeted protein degradation in research and therapeutic contexts.
Product Information
Catalog NumA60236
FormulaC41H54O5
Molecular Weight626.86
CAS Number1326612-12-7
SMILESO[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCCC(C)(C)OC(C4=CC=CC=C4)=O)C)([H])[C@@]5(C(C[C@H](CC5)OC(C6=CC=CC=C6)=O)=C1)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > Ligand for Target Protein for PROTAC