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8-Aza-7-bromo-7-deazaguanosine

Purine Nucleoside Analog

8-Aza-7-bromo-7-deazaguanosine is a purine nucleoside analog that effectively targets DNA synthesis pathways. It exhibits significant antitumor activity, particularly in the context of indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. This compound is valuable for researchers investigating mechanisms of cancer treatment and the role of nucleoside analogs in therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	96555-37-2
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₂BrN₅O₅
Molecular Weight	362.14
SMILES	OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3C(Br)=N2)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.