8-Br-2'-O-Me-cAMP

Catalog No.: A63644
cAMP Analogue
8-Br-2'-O-Me-cAMP is a synthetic analog of cyclic AMP (cAMP) that selectively activates exchange factors activated by cAMP (Epac) without stimulating protein kinase A (PKA). This unique property makes it a valuable tool for investigating cAMP-mediated signaling pathways. It is particularly relevant in studies related to cardiovascular diseases, facilitating the exploration of Epac's role in cardiac function and pathology.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description8-Br-2'-O-Me-cAMP is a synthetic analog of cyclic AMP (cAMP) that selectively activates exchange factors activated by cAMP (Epac) without stimulating protein kinase A (PKA). This unique property makes it a valuable tool for investigating cAMP-mediated signaling pathways. It is particularly relevant in studies related to cardiovascular diseases, facilitating the exploration of Epac's role in cardiac function and pathology.
Product Information
Catalog NumA63644
FormulaC11H13BrN5O6P
Molecular Weight422.13
CAS Number612513-13-0
SMILESNC1=NC=NC2=C1N=C(Br)N2[C@@H]3O[C@H](CO4)[C@@H](OP4(O)=O)[C@H]3OC
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