Fig. 1 · Structure
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8-Iodooct-1-yne
PROTAC Linker
8-Iodooct-1-yne is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a critical component in the synthesis of PROTACs, enabling targeted degradation of specific proteins. Its utility in research applications includes the exploration of protein regulation and degradation pathways, offering significant potential in therapeutic development and chemical biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 60754-50-9 |
| Applications | PROTAC Linker |
| Formula | C8H13I |
| Molecular Weight | 236.10 |
| SMILES | ICCCCCCC#C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.