Fig. 1 · Structure
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8-iso-15-keto Prostaglandin F2α
TP Agonist
8-iso-15-keto Prostaglandin F2α is a partial agonist targeting the Thromboxane receptor (TP). It demonstrates notable vasoconstrictive activity with a pD2 value of 5.8. Additionally, at elevated concentrations, this compound can induce mild relaxation effects in rat aorta rings, making it relevant for studies in vascular biology and related research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 191919-01-4 |
| Applications | TP Agonist |
| Formula | C20H32O5 |
| Molecular Weight | 352.47 |
| Synonyms | 8-iso-15-keto PGF2α |
| SMILES | OC(CCC/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/C(CCCCC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.