Fig. 1 · Structure
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8-iso Prostaglandin F3α
Prostaglandin Receptor
8-iso Prostaglandin F3α is an isoprostane generated from the free-radical peroxidation of eicosapentaenoic acid (EPA). The compound primarily interacts with prostaglandin receptors, although its overall biological activity remains largely unexplored. A notable study indicates that 8-iso PGF3α is inactive in thromboxane receptor-mediated assays, such as those evaluating human platelet shape change, in contrast to its isoform 8-iso PGF2α, which exhibits an effective concentration of 1 μM. This suggests potential avenues for investigating its role in lipid peroxidation-related processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 7045-31-0 |
| Applications | Prostaglandin Receptor |
| Formula | C20H32O5 |
| Molecular Weight | 352.47 |
| Synonyms | 8-epi PGF3α; 8-iso PGF3α |
| SMILES | O[C@@H]1[C@H]([C@H]([C@@H](C1)O)/C=C/[C@H](C/C=C\CC)O)C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.