Fig. 1 · Structure
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8-Isoprostaglandin E2
Thromboxane A2 Receptor Ligand
8-Isoprostaglandin E2 (iPE2-III) is a potent ligand for the thromboxane A2 receptor (TP). It is known to induce vasoconstriction and promote platelet aggregation, making it significant in vascular biology and hemostasis research. Additionally, 8-Isoprostaglandin E2 enhances the RANKL-dependent osteoclastic activity of marrow hematopoietic precursors through the cAMP signaling pathway, positioning it as a valuable agent in studies of bone metabolism and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 27415-25-4 |
| Applications | Thromboxane A2 Receptor Ligand |
| Formula | C20H32O5 |
| Molecular Weight | 352.47 |
| Synonyms | iPE2-III |
| SMILES | CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.