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8-NBD-cAMP sodium

Fluorescence Indicator

8-NBD-cAMP sodium is a fluorescently labeled analogue of cyclic adenosine monophosphate (cAMP) that serves as a valuable tool for studying cAMP signaling pathways. It retains the biological activity of cAMP by binding to key proteins such as exchange protein directly activated by cAMP (EPAC) and protein kinase A (PKA). This reagent is particularly useful in fluorescent competitive binding assays to assess the binding affinity of novel EPAC1 agonists for EPAC1 proteins, facilitating research in cellular signaling and pharmacology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	221905-51-7
Applications	Fluorescence Indicator
Formula	C₁₈H₁₇N₉NaO₉PS
Molecular Weight	589.41
SMILES	NC1=C(N=C2SCCNC3=CC=C([N+]([O-])=O)C4=NON=C43)C(N2[C@@]5([H])[C@H](O)[C@@](OP(OC6)(O[Na])=O)([H])[C@]6([H])O5)=NC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.