Fig. 1 · Structure
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8-Nitroguanosine
Guanosine Analog
8-Nitroguanosine is a guanosine analog that exerts immunostimulatory activity. It has been shown to induce type I interferons in various animal models, leading to notable antiviral effects. The biological activity of 8-Nitroguanosine is primarily mediated through the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research in antiviral response and immune modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 337536-53-5 |
| Applications | Guanosine Analog |
| Formula | C10H12N6O7 |
| Molecular Weight | 328.24 |
| SMILES | O[C@H]1[C@@H](O)[C@H](N(C([N+]([O-])=O)=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.