Fig. 1 · Structure
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8-Pcpt-cGMP sodium
CNG Channel Agonist
8-Pcpt-cGMP sodium is a potent agonist of cyclic nucleotide-gated (CNG) channels, displaying an EC50 of 0.5 μM. Its favorable membrane permeability enables effective cellular uptake, making it an ideal tool for research into the mechanisms of CNG channels. This compound is particularly valuable for studies focused on visual signal transduction and olfactory transduction pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 51239-26-0 |
| Applications | CNG Channel Agonist |
| Formula | C16H14ClN5NaO7PS |
| Molecular Weight | 509.79 |
| SMILES | O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O[Na])=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.