Fig. 1 · Structure
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8-Pcpt-cGMP
CNG Channel Agonist
8-Pcpt-cGMP is a potent agonist for cyclic nucleotide-gated (CNG) channels, exhibiting an EC50 of 0.5 μM. This compound demonstrates excellent membrane permeability, facilitating its application in biological studies. 8-Pcpt-cGMP is commonly utilized in research investigating the role of CNG channels in visual signal transduction and olfactory transduction pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 54364-02-2 |
| Applications | CNG Channel Agonist |
| Formula | C16H15ClN5O7PS |
| Molecular Weight | 487.81 |
| SMILES | O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O)=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.