Fig. 1 · Structure

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8-(tert-Butoxy)-8-oxooctanoic acid

PROTAC Linker

8-(tert-Butoxy)-8-oxooctanoic acid serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras. Its structure allows for efficient conjugation to target proteins, enhancing the selective degradation of unwanted proteins within cells. This compound is instrumental in biochemical research applications focused on protein modulation and cellular pathway regulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 234081-94-8
Applications PROTAC Linker
Formula C12H22O4
Molecular Weight 230.30
SMILES
O=C(O)CCCCCCC(=O)OC(C)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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