Fig. 1 · Structure
Documents & Downloads
8RK64
UCHL1 Inhibitor
8RK64 is a potent covalent inhibitor of UCHL1, demonstrating an IC50 value of 0.32 μM. This compound serves as a versatile click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, 8RK64 can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when paired with DBCO or BCN functionalized compounds. Its applications span chemical biology, enabling the study of UCHL1's role in cellular processes and potential therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2705841-52-5 |
| Applications | UCHL1 Inhibitor |
| Formula | C14H16N8O2S |
| Molecular Weight | 360.39 |
| SMILES | N#CN1CC[C@@H](C1)C(NC2=NC3=C(S2)CN(CC3)C(CN=[N+]=[N-])=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.