Fig. 1 · Structure
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9-deoxy-9-methylene Prostaglandin E2
Prostaglandin Receptor
9-deoxy-9-methylene Prostaglandin E2 is a stable isosteric analog of Prostaglandin E2 (PGE2) targeting prostaglandin receptors. It exhibits similar biological activity to PGE2 while demonstrating a reduced side effect profile. Research indicates that 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in lowering blood pressure in rats and effectively stimulates colonic activity in gerbils as well as uterine contractions in primates, making it valuable for studies on cardiovascular and reproductive physiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 61263-32-9 |
| Applications | Prostaglandin Receptor |
| Formula | C21H34O4 |
| Molecular Weight | 350.49 |
| Synonyms | 9-Deoxy-9-methylene PGE2 |
| SMILES | O[C@H]1[C@@H]([C@H](C(C1)=C)C/C=C\CCCC(O)=O)/C=C/[C@H](CCCCC)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.