Fig. 1 · Structure
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9(R)-HETE
Drug Isomer
9(R)-HETE is an enantiomer of 9-HETE, comprising 50% of the racemic mixture (±)9-HETE. It functions as an activator of RXRγ-dependent transcription, demonstrating a 1.5-fold increase in activity at a concentration of 300 nM compared to controls. The stereochemical characterization of the (R) enantiomer is supported by chiral HPLC retention time comparisons with published data. This compound is valuable for studies investigating RXR signaling pathways and lipid metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 107656-14-4 |
| Applications | Drug Isomer |
| Formula | C20H32O3 |
| Molecular Weight | 320.47 |
| Synonyms | 9(R)-Hydroxyeicosatetraenoic acid |
| SMILES | CCCCC/C=C\C/C=C\C[C@@H](O)/C=C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.